One of the most severe—and misunderstood—types of traumatic brain injury (TBI) is the diffuse axonal injury (DAI). Diffuse axonal injuries occur when the brain's nerve fibers, or axons, tear as the brain shifts in the skull. This can happen when the brain is shaken within the skull, as in cases involving motor vehicle accidents or after blunt-force trauma injuries to the brain.

DAIs create microscopic changes within the brain; these tiny changes may not be captured through magnetic resonance imaging (MRI) or computed tomography (CT) scans. This blog aims to shed light on what DAIs are, why they occur, and why they often go undetected in standard imaging tests.

If you believe you have a diffuse axonal injury, call the traumatic brain injury lawyers at the Poole Law Group for a free, comprehensive consultation: 301-790-3600

Read More: 5 Symptoms of Traumatic Brain Injury

Diffuse Axonal Injury Diagram

Diffuse Axonal Injuries: A Brief Overview

Diffuse Axonal Injury (DAI) is a form of traumatic brain injury that occurs when the brain rapidly shifts inside the skull as a result of acceleration or deceleration forces. Diffuse axonal injuries are characterized by widespread damage across multiple areas of brain tissue, as the combination of forces can cause extensive lesions in white matter tracts over several parts of the brain. 

Causes of Diffuse Axonal Injuries

Diffuse axonal injuries are typically caused by high-speed motor vehicle accidents, falls, sports-related injuries, and assaults. DAI is also common in cases of shaken baby syndrome. 

The rapid movement of the brain within the skull causes axons (the long, threadlike part of a nerve cell along which impulses are conducted) to stretch and tear. This shearing force can create intracranial pressure, as well as damage to brain cells and blood vessels; this can disrupt normal brain function and can lead to severe, long-term neurological impairment.

Symptoms of Diffuse Axonal Injuries

Symptoms of diffuse axonal injuries can vary widely depending on the severity and extent of the injury. This may include:

    • Loss of consciousness (ranging from minutes to prolonged coma)

    • Cognitive impairments, including post-traumatic stress disorder

    • Motor function deficits

    • Sensory processing issues

    • Behavioral changes

Diagnosing diffuse axonal injuries can be challenging because of the nature of the injury; damage may be spread throughout the brain, including the midbrain (corpus callosum). Traditional imaging methods such as CT scans and standard MRIs may not always detect the subtle changes associated with diffuse axonal injuries.

Diffuse Axonal Injury Scan

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Standard Imaging May Miss Diffuse Axonal Injuries

The severity of a traumatic brain injury is ranked on the Glasgow Coma Scale, ranging from mild traumatic brain injury (mTBI), also called a concussion, to severe. Even in cases of severe traumatic brain injury, however, commonly used diagnostic tools may miss indicators of a diffuse axonal injury. 

Why are diffuse axonal injuries so hard to diagnose? We recognize three common reasons:

  1. Subtle Lesions: Diffuse axonal injuries cause microscopic damage to the brain's axons, which may not be easily visible on standard imaging tests. While CT scans can detect bleeding, swelling, and other risk factors, they may not show the tiny shearing injuries that characterize diffuse axonal injuries.

  2. Resolution Limitations: Standard MRI scans have limited resolution and may miss the fine, diffuse changes in white matter tracts. Advanced imaging techniques like Diffusion Tensor Imaging (DTI) are more sensitive to these changes but are not always used in initial assessments.

  3. Diffuse Nature: The widespread and scattered nature of the damage in diffuse axonal injuries means that there may not be a single, identifiable area of injury. This diffuse pattern can make it difficult for standard imaging to capture the full extent of the injury.

Advanced Imaging Techniques

While it can be challenging to detect with standard imaging techniques, advancements in neuroimaging are improving our ability to diagnose and understand this condition. For a more accurate diagnosis of diffuse axonal injuries, advanced imaging techniques are often required:

  • Diffusion Tensor Imaging (DTI): This specialized form of MRI measures the movement of water molecules in the brain’s white matter. It can detect disruptions in the normal flow, indicating areas of axonal injury.

  • Functional MRI (fMRI): fMRI can assess brain activity by measuring changes in blood flow, helping to identify areas of the brain that are not functioning properly.

  • Magnetic Resonance Spectroscopy (MRS): MRS can detect changes in brain metabolism, providing insights into the biochemical effects of diffuse axonal injuries.

Legal Implications of Diffuse Axonal Injuries

For people who have sustained a traumatic brain injury, and suspect that they may have a DAI, it is essential to seek out a medical diagnosis that can exhaustively rule out this condition. Look for a medical provider who is familiar with advanced imaging techniques, and do so as soon after your injury as possible. 

Proper diagnosis and documentation are critical for building a strong legal case; this will set the groundwork for compensation related to your medical expenses, rehabilitation costs, and pain and suffering resulting from a DAI.

If you or a loved one has suffered a DAI, seeking comprehensive medical evaluation and legal counsel is essential for navigating the path to recovery and justice. Call the Poole Law Group today to set up your free consultation: 301-790-3600

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